Advancements in Hydrogel-Based Drug Sustained Release Systems for Bone Tissue Engineering
نویسندگان
چکیده
منابع مشابه
pH Sensitive Hydrogel Based Acrylic Acid for Controlled Drug Release
Hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. The present study aims to create a controlled-release system through the preparation and characterization of hydrogels based on pH-sensitive polymers such as poly (acrylic acid). Poly (acrylic acid), p(AA), hydrogel has been synthesized by radical po...
متن کاملSustained Release of Risedronate from PLGA Microparticles Embedded in Alginate Hydrogel for Treatment of Bony Lesions
Background: Inflammatory bone resorption in periodontitis can lead to tooth loss. Systemic administration of bisphosphonates such as risedronate for preventing bone resorption can cause adverse effects. Alginate hydrogel (ALG) and poly (lactic acid-co-glycolic acid) (PLGA) microparticles have been studied as drug delivery systems for sustained release of drugs. Therefore, the release pattern of...
متن کاملph sensitive hydrogel based acrylic acid for controlled drug release
hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. the present study aims to create a controlled-release system through the preparation and characterization of hydrogels based on ph-sensitive polymers such as poly (acrylic acid). poly (acrylic acid), p(aa), hydrogel has been synthesized by radical po...
متن کاملCurrent Concepts in Scaffolding for Bone Tissue Engineering
Bone disorders are of significant worry due to their increased prevalence in the median age. Scaffold-based bonetissue engineering holds great promise for the future of osseous defects therapies. Porous composite materials andfunctional coatings for metallic implants have been introduced in next generation of orthopedic medicine for tissueengineering. While osteoconductive materials such as hyd...
متن کاملPolycaprolactone scaffold engineered for sustained release of resveratrol: therapeutic enhancement in bone tissue engineering
Biomaterials-based three-dimensional scaffolds are being extensively investigated in bone tissue engineering. A potential scaffold should be osteoconductive, osteoinductive, and osteogenic for enhanced bone formation. In this study, a three-dimensional porous polycapro-lactone (PCL) scaffold was engineered for prolonged release of resveratrol. Resveratrol-loaded albumin nanoparticles (RNP) were...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2020
ISSN: 1663-9812
DOI: 10.3389/fphar.2020.00622